PT Unknown
AU Pan, W
TI Epigenetic marks of a stable host-microbiota association in the mammalian gut
PY 2017
PU Christian-Albrechts-Universität zu Kiel
WP https://macau.uni-kiel.de/receive/diss_mods_00021580
LA de
DE Gut microbiota; IBD; inflammation; DNA methylation; intestine epithelial cell; transcriptome; host-microbiota interaction
AB To summarize, the results shown here confirms that the host-microbiota interaction is a critical check pint for intestinal inflammation and development. Though, it is still a debate whether the interaction is a cause or consequence of the disease, the results indicate a potential role of epigenetic modification in disease manifestation of UC or postnatal development. The finding might be helpful to support the combinational epigenetic and microbiota based therapies of intestine inflammation.
PI Kiel
ER