000K  utf8
1100  $c2019
1500  eng
2050  urn:nbn:de:gbv:8-mods-2019-00009-0
3000  Makowka, Alexander
4000  Glycolytic shunts are anaplerotic reactions for the Calvin-Benson-Bassham cycle$hChristian-Albrechts-Universität zu Kiel  [Makowka, Alexander]
4000  Glykolytische Shunts sind anaplerotische Reaktionen für den Calvin-Benson-Bassham Zyklus$hChristian-Albrechts-Universität zu Kiel  [Makowka, Alexander]
4030  Kiel$nChristian-Albrechts-Universität zu Kiel
4209  In this work, it was shown that the cyanobacterium Synechocystis employs three glycolytic shunts as anaplerotic reactions for the CBB cycle. The three shunts, named 'PGI shunt', 'OPP shunt' and 'ED shunt', not only mediated anaplerosis of glucose that was taken up under mixotrophic conditions but also of glycogen-derived glucose under photoautotrophic conditions. It could be shown that degradation of glycogen was able to improve restarting of the CBB cycle after a period of darkness. This suggests, that the cellular glycogen pool in cyanobacteria functions as a metabolic buffer that can be tapped upon demand in order to improve flux in the CBB cycle. The three glycolytic shunts thereby function as anaplerotic reactions. It can be assumed that glycolytic shunts not only help to control metabolite stoichiometry in the CBB cycle, but also to influence the cellular ATP and NADPH pools and thus provide a tool to improve synchronization with the photosynthetic light reaction.
4950  https://nbn-resolving.org/urn:nbn:de:gbv:8-mods-2019-00009-0$xR$3Volltext$534
4961  https://macau.uni-kiel.de/receive/macau_mods_00000018
5051  580
5550  6803
5550  anaplerotic
5550  autocatalytic
5550  Benson
5550  Calvin
5550  Calvin-Benson
5550  Calvin-Benson-Bassham
5550  CBB
5550  cyanobacteria
5550  cycle
5550  ED
5550  Entner
5550  Entner-Doudoroff
5550  OPP
5550  PGI
5550  Synechocystis