@Article{macau_mods_00000590,
  author = 	{Geritz, Johanna
		and Maetzold, Sara
		and Steffen, Maren
		and Pilotto, Andrea
		and Corr{\`a}, Marta F.
		and Moscovich, Mariana
		and Rizzetti, Maria C.
		and Borroni, Barbara
		and Padovani, Alessandro
		and Alpes, Annekathrin
		and Bang, Corinna
		and Barcellos, Igor
		and Baron, Ralf
		and Bartsch, Thorsten
		and Becktepe, Jos S.
		and Berg, Daniela
		and Bergeest, Lu M.
		and Bergmann, Philipp
		and Bou{\c{c}}a-Machado, Raquel
		and Drey, Michael
		and Elshehabi, Morad
		and Farahmandi, Susan
		and Ferreira, Joaquim J.
		and Franke, Andre
		and Friederich, Anja
		and Geisler, Corinna
		and H{\"u}llemann, Philipp
		and Gierthm{\"u}hlen, Janna
		and Granert, Oliver
		and Heinzel, Sebastian
		and Heller, Maren K.
		and Hobert, Markus A.
		and Hofmann, Marc
		and Jemlich, Bj{\"o}rn
		and Kerkmann, Laura
		and Kn{\"u}pfer, Stephanie
		and Krause, Katharina
		and Kress, Maximilian
		and Krupp, Sonja
		and Kudelka, Jennifer
		and Kuhlenb{\"a}umer, Gregor
		and Kurth, Roland
		and Leypoldt, Frank
		and Maetzler, Corinna
		and Maia, Luis F.
		and Moewius, Andreas
		and Neumann, Patricia
		and Niemann, Katharina
		and Ortlieb, Christian T.
		and Paschen, Steffen
		and Pham, Hoang Minh
		and Puehler, Thomas
		and Radloff, Franziska
		and Riedel, Christian
		and Rogalski, Marten
		and Sablowsky, Simone
		and Schanz, Elena M.
		and Schebesta, Linda
		and Schicketm{\"u}ller, Andreas
		and Studt, Simone
		and Thieves, Martina
		and T{\"o}nges, Lars
		and Ullrich, Sebastian
		and Urban, Peter P.
		and Vila-Ch{\~a}, Nuno
		and Wiegard, Anna
		and Warmerdam, Elke
		and Warnecke, Tobias
		and Wei{\ss}, Michael
		and Welzel, Julius
		and Hansen, Clint
		and Maetzler, Walter},
  title = 	{Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study},
  journal = 	{BMC geriatrics},
  year = 	{2020},
  publisher = 	{BioMed Central},
  address = 	{London},
  number = 	{20},
  keywords = 	{Balance; Body-worn sensors; Wearables; Comprehensive geriatric assessment; Executive function; Gait; Older adults; Quantitative assessment},
  abstract = 	{Background: Motor and cognitive deficits and consequently mobility problems are common in geriatric patients. The currently available methods for diagnosis and for the evaluation of treatment in this vulnerable cohort are limited. The aims of the ComOn (COgnitive and Motor interactions in the Older populatioN) study are (i) to define quantitative markers with clinical relevance for motor and cognitive deficits, (ii) to investigate the interaction between both motor and cognitive deficits and (iii) to assess health status as well as treatment outcome of 1000 geriatric inpatients in hospitals of Kiel (Germany), Brescia (Italy), Porto (Portugal), Curitiba (Brazil) and Bochum (Germany). Methods: This is a prospective, explorative observational multi-center study. In addition to the comprehensive geriatric assessment, quantitative measures of reduced mobility and motor and cognitive deficits are performed before and after a a two week's inpatient stay. Components of the assessment are mobile technology-based assessments of gait, balance and transfer performance, neuropsychological tests, frailty, sarcopenia, autonomic dysfunction and sensation, and questionnaires to assess behavioral deficits, activities of daily living, quality of life, fear of falling and dysphagia. Structural MRI and an unsupervised 24/7 home assessment of mobility are performed in a subgroup of participants. The study will also investigate the minimal clinically relevant change of the investigated parameters. Diskussion: This study will help form a better understanding of symptoms and their complex interactions and treatment effects in a large geriatric cohort.},
  issn = 	{1471-2318},
  doi = 	{10.1186/s12877-020-1445-z},
  url = 	{https://macau.uni-kiel.de/receive/macau_mods_00000590},
  url = 	{https://doi.org/10.1186/s12877-020-1445-z},
  file = 	{:https://macau.uni-kiel.de/servlets/MCRFileNodeServlet/macau_derivate_00001616/10.1186@s12877-020-1445-z.pdf:PDF},
  language = 	{en}
}