PT Journal
AU Geritz, J
   Maetzold, S
   Steffen, M
   Pilotto, A
   Corrà, MF
   Moscovich, M
   Rizzetti, MC
   Borroni, B
   Padovani, A
   Alpes, A
   Bang, C
   Barcellos, I
   Baron, R
   Bartsch, T
   Becktepe, JS
   Berg, D
   Bergeest, LM
   Bergmann, P
   Bouça-Machado, R
   Drey, M
   Elshehabi, M
   Farahmandi, S
   Ferreira, JJ
   Franke, A
   Friederich, A
   Geisler, C
   Hüllemann, P
   Gierthmühlen, J
   Granert, O
   Heinzel, S
   Heller, MK
   Hobert, MA
   Hofmann, M
   Jemlich, B
   Kerkmann, L
   Knüpfer, S
   Krause, K
   Kress, M
   Krupp, S
   Kudelka, J
   Kuhlenbäumer, G
   Kurth, R
   Leypoldt, F
   Maetzler, C
   Maia, LF
   Moewius, A
   Neumann, P
   Niemann, K
   Ortlieb, CT
   Paschen, S
   Pham, HM
   Puehler, T
   Radloff, F
   Riedel, C
   Rogalski, M
   Sablowsky, S
   Schanz, EM
   Schebesta, L
   Schicketmüller, A
   Studt, S
   Thieves, M
   Tönges, L
   Ullrich, S
   Urban, PP
   Vila-Chã, N
   Wiegard, A
   Warmerdam, E
   Warnecke, T
   Weiß, M
   Welzel, J
   Hansen, C
   Maetzler, W
TI Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study
SO BMC geriatrics
PY 2020
IS 20
PU BioMed Central
DI 10.1186/s12877-020-1445-z
WP https://macau.uni-kiel.de/receive/macau_mods_00000590
LA en
DE Balance; Body-worn sensors; Wearables; Comprehensive geriatric assessment; Executive function; Gait; Older adults; Quantitative assessment
SN 1471-2318
AB Background: Motor and cognitive deficits and consequently mobility problems are common in geriatric patients. The currently available methods for diagnosis and for the evaluation of treatment in this vulnerable cohort are limited. The aims of the ComOn (COgnitive and Motor interactions in the Older populatioN) study are (i) to define quantitative markers with clinical relevance for motor and cognitive deficits, (ii) to investigate the interaction between both motor and cognitive deficits and (iii) to assess health status as well as treatment outcome of 1000 geriatric inpatients in hospitals of Kiel (Germany), Brescia (Italy), Porto (Portugal), Curitiba (Brazil) and Bochum (Germany). Methods: This is a prospective, explorative observational multi-center study. In addition to the comprehensive geriatric assessment, quantitative measures of reduced mobility and motor and cognitive deficits are performed before and after a a two week's inpatient stay. Components of the assessment are mobile technology-based assessments of gait, balance and transfer performance, neuropsychological tests, frailty, sarcopenia, autonomic dysfunction and sensation, and questionnaires to assess behavioral deficits, activities of daily living, quality of life, fear of falling and dysphagia. Structural MRI and an unsupervised 24/7 home assessment of mobility are performed in a subgroup of participants. The study will also investigate the minimal clinically relevant change of the investigated parameters. Diskussion: This study will help form a better understanding of symptoms and their complex interactions and treatment effects in a large geriatric cohort.
PI London
ER