000K utf8 1100 $c2020 1500 eng 2050 urn:nbn:de:gbv:8-mods-2020-00237-7 2051 10.1186/s12877-020-1445-z 3000 Geritz, Johanna 3010 Alpes, Annekathrin 3010 Bang, Corinna 3010 Barcellos, Igor 3010 Baron, Ralf 3010 Bartsch, Thorsten 3010 Becktepe, Jos S. 3010 Berg, Daniela 3010 Bergeest, Lu M. 3010 Bergmann, Philipp 3010 Borroni, Barbara 3010 Bouça-Machado, Raquel 3010 Corrà, Marta F. 3010 Drey, Michael 3010 Elshehabi, Morad 3010 Farahmandi, Susan 3010 Ferreira, Joaquim J. 3010 Franke, Andre 3010 Friederich, Anja 3010 Geisler, Corinna 3010 Gierthmühlen, Janna 3010 Granert, Oliver 3010 Hansen, Clint 3010 Heinzel, Sebastian 3010 Heller, Maren K. 3010 Hobert, Markus A. 3010 Hofmann, Marc 3010 Hüllemann, Philipp 3010 Jemlich, Björn 3010 Kerkmann, Laura 3010 Knüpfer, Stephanie 3010 Krause, Katharina 3010 Kress, Maximilian 3010 Krupp, Sonja 3010 Kudelka, Jennifer 3010 Kuhlenbäumer, Gregor 3010 Kurth, Roland 3010 Leypoldt, Frank 3010 Maetzler, Corinna 3010 Maetzler, Walter 3010 Maetzold, Sara 3010 Maia, Luis F. 3010 Moewius, Andreas 3010 Moscovich, Mariana 3010 Neumann, Patricia 3010 Niemann, Katharina 3010 Ortlieb, Christian T. 3010 Padovani, Alessandro 3010 Paschen, Steffen 3010 Pham, Hoang Minh 3010 Pilotto, Andrea 3010 Puehler, Thomas 3010 Radloff, Franziska 3010 Riedel, Christian 3010 Rizzetti, Maria C. 3010 Rogalski, Marten 3010 Sablowsky, Simone 3010 Schanz, Elena M. 3010 Schebesta, Linda 3010 Schicketmüller, Andreas 3010 Steffen, Maren 3010 Studt, Simone 3010 Thieves, Martina 3010 Tönges, Lars 3010 Ullrich, Sebastian 3010 Urban, Peter P. 3010 Vila-Chã, Nuno 3010 Warmerdam, Elke 3010 Warnecke, Tobias 3010 Weiß, Michael 3010 Welzel, Julius 3010 Wiegard, Anna 4000 Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study [Geritz, Johanna] 4209 Background: Motor and cognitive deficits and consequently mobility problems are common in geriatric patients. The currently available methods for diagnosis and for the evaluation of treatment in this vulnerable cohort are limited. The aims of the ComOn (COgnitive and Motor interactions in the Older populatioN) study are (i) to define quantitative markers with clinical relevance for motor and cognitive deficits, (ii) to investigate the interaction between both motor and cognitive deficits and (iii) to assess health status as well as treatment outcome of 1000 geriatric inpatients in hospitals of Kiel (Germany), Brescia (Italy), Porto (Portugal), Curitiba (Brazil) and Bochum (Germany). Methods: This is a prospective, explorative observational multi-center study. In addition to the comprehensive geriatric assessment, quantitative measures of reduced mobility and motor and cognitive deficits are performed before and after a a two week's inpatient stay. Components of the assessment are mobile technology-based assessments of gait, balance and transfer performance, neuropsychological tests, frailty, sarcopenia, autonomic dysfunction and sensation, and questionnaires to assess behavioral deficits, activities of daily living, quality of life, fear of falling and dysphagia. Structural MRI and an unsupervised 24/7 home assessment of mobility are performed in a subgroup of participants. The study will also investigate the minimal clinically relevant change of the investigated parameters. Diskussion: This study will help form a better understanding of symptoms and their complex interactions and treatment effects in a large geriatric cohort. 4950 https://doi.org/10.1186/s12877-020-1445-z$xR$3Volltext$534 4950 https://nbn-resolving.org/urn:nbn:de:gbv:8-mods-2020-00237-7$xR$3Volltext$534 4961 https://macau.uni-kiel.de/receive/macau_mods_00000590 5051 610 5550 Balance 5550 Body-worn sensors 5550 Comprehensive geriatric assessment 5550 Executive function 5550 Gait 5550 Older adults 5550 Quantitative assessment 5550 Wearables