000K utf8 1100 $c2022 1500 eng 2050 urn:nbn:de:gbv:8:3-2023-00620-8 2051 10.1364/BOE.475358 3000 Titov, Igor 3010 Gerken, Martina 3010 Köpke, Markus 3010 Kraft, Fabio Aldo 3010 Nebling, Eric 3010 Rutschke, Nils 4000 Detection of fluorescence-labeled DNA with in-plane organic optoelectronic devices [Titov, Igor] 4209 We present a system efficiency analysis of a monolithic integrated organic optoelectronic unit for the detection of fluorescence labeled single-stranded DNA (ssDNA) for veterinary disease testing. The side-by-side integration of an organic light emitting diode (OLED) and an organic photodetector (OPD) with 0.5 mm by 0.5 mm device sizes has the potential to enable compact and low-cost fluorescence point-of-care (POC) devices for decentral multiplex biomedical testing. Here, we used two 6-FAM and BHQ1 labeled complementary ssDNA strands to form the Förster resonance transfer (FRET) upon the hybridization of the DNA. In this work we successfully show ssDNA hybridization sensing with samples diluted in TE buffer and investigate the detection of covalently bound 6-FAM-ssDNA on a glass surface for multiplex biomarker measurements. 4950 https://doi.org/10.1364/BOE.475358$xR$3Volltext$534 4950 https://nbn-resolving.org/urn:nbn:de:gbv:8:3-2023-00620-8$xR$3Volltext$534 4961 https://macau.uni-kiel.de/receive/macau_mods_00003943 5051 600 5550 fluorescence 5550 Förster resonance transfer (FRET) 5550 measurements 5550 multiplex biomarker 5550 optoelectronic 5550 single-stranded DNA (ssDNA)