000K utf8 1100 $c2022 1500 eng 2050 urn:nbn:de:gbv:8:3-2024-00317-8 2051 10.1007/s00415-022-11000-6 3000 Nydahl, Peter 3010 Baumgarte, Friederike 3010 Berg, Daniela Dagmar Denise 3010 Bergjan, Manuela 3010 Borzikowsky, Christoph 3010 Franke, Christiana 3010 Green, Diana 3010 Hannig, Anisa 3010 Hansen, Hans Christian 3010 Hansen, Uta 3010 Hauss, Armin 3010 Istel, Rahel 3010 Krämer, Norma 3010 Krause, Karita 3010 Lohrmann, Renée 3010 Margraf, Nils G 3010 Meyne, Johannes 3010 Mohammadzadeh-Vazifeh, Mohammad 3010 Osterbrink, Jürgen 3010 Palm, Frederick 3010 Petersen, Telse 3010 Schöller, Bernd 3010 Stolze, Henning 3010 Zilezinski, Max 4000 Delirium on stroke units: a prospective, multicentric quality-improvement project$hSpringer Science and Business Media LLC [Nydahl, Peter] 4030 $nSpringer Science and Business Media LLC 4209 Background Post-stroke delirium (POD) in patients on stroke units (SU) is associated with an increased risk for complications and poorer clinical outcome. The objective was to reduce the severity of POD by implementing an interprofessional delirium-management. Methods Multicentric quality-improvement project on five SU implementing a delirium-management with pre/post-comparison. Primary outcome was severity of POD, assessed with the Nursing Delirium Screening Scale (Nu-DESC). Secondary outcome parameters were POD incidence, duration, modified Rankin Scale (mRS), length of stay in SU and hospital, mortality, and others. Results Out of a total of 799 patients, 59.4% (n = 475) could be included with 9.5% (n = 45) being delirious. Implementation of a delirium-management led to reduced POD severity; Nu-DESC median: pre: 3.5 (interquartile range 2.6-4.7) vs. post 3.0 (2.2-4.0), albeit not significant (p = 0.154). Other outcome parameters were not meaningful different. In the post-period, delirium-management could be delivered to 75% (n = 18) of delirious patients, and only 24 (53.3%) of delirious patients required pharmacological treatments. Patients with a more severe stroke and POD remained on their disability levels, compared to similar affected, non-delirious patients who improved. Conclusions Implementation of delirium-management on SU is feasible and can be delivered to most patients, but with limited effects. Nursing interventions as first choice could be delivered to the majority of patients, and only the half required pharmacological treatments. Delirium-management may lead to reduced severity of POD but had only partial effects on duration of POD or length of stay. POD hampers rehabilitation, especially in patients with more severe stroke. Registry DRKS, DRKS00021436. Registered 04/17/2020, www.drks.de/DRKS00021436 . 4950 https://doi.org/10.1007/s00415-022-11000-6$xR$3Volltext$534 4950 https://nbn-resolving.org/urn:nbn:de:gbv:8:3-2024-00317-8$xR$3Volltext$534 4961 https://macau.uni-kiel.de/receive/macau_mods_00004599 5051 610 5550 Delirium 5550 Delirium 5550 encephalopathy 5550 Humans 5550 Incidence 5550 Postoperative Complications 5550 Prospective Studies 5550 Quality Improvement 5550 Quality-improvement 5550 Registries 5550 Risk Factors 5550 Stroke 5550 Stroke