000K utf8 1100 $c2015 1500 eng 2050 urn:nbn:de:gbv:8-publ-23538 2051 10.3389/fneur.2015.00216 3000 Reijs, Babette L. R. 3010 Baldeiras, Inês 3010 Betsou, Fay 3010 Blennow, Kaj 3010 Brosseron, Frederic 3010 Cavedo, Enrica 3010 de Mendonça, Alexandre 3010 Fladby, Tormod 3010 Froelich, Lutz 3010 Gabryelewicz, Tomasz 3010 Goncharenko, Nikolai 3010 Gurvit, Hakan 3010 Kapaki, Elisabeth 3010 Koson, Peter 3010 Kulic, Luka 3010 Lehmann, Sylvain 3010 Lewczuk, Piotr 3010 Lleó, Alberto 3010 Mätzler, Walter 3010 Miller, Anne-Marie 3010 Molinuevo, José L. 3010 Mollenhauer, Brit 3010 Parnetti, Lucilla 3010 Rot, Uros 3010 Scheltens, Philip 3010 Schneider, Anja 3010 Simonsen, Anja Hviid 3010 Tagliavini, Fabrizio 3010 Teunissen, Charlotte E. 3010 Tsolaki, Magda 3010 Verbeek, Marcel M. 3010 Verhey, Frans R. J. 3010 Visser, Pieter Jelle 3010 Winblad, Bengt 3010 Zboch, Marzena 3010 Zetterberg, Henrik 4000 The Central Biobank and Virtual Biobank of BIOMARKAPD: A Resource for Studies on Neurodegenerative Diseases [Reijs, Babette L. R.] 4209 Biobanks are important resources for biomarker discovery and assay development. Biomarkers for Alzheimer's and Parkinson's disease (BIOMARKAPD) is a European multicenter study, funded by the EU Joint Programme-Neurodegenerative Disease Research, which aims to improve the clinical use of body fluid markers for the diagnosis and prognosis of Alzheimer's disease (AD) and Parkinson's disease (PD). The objective was to standardize the assessment of existing assays and to validate novel fluid biomarkers for AD and PD. To support the validation of novel biomarkers and assays, a central and a virtual biobank for body fluids and associated data from subjects with neurodegenerative diseases have been established. In the central biobank, cerebrospinal fluid (CSF) and blood samples were collected according to the BIOMARKAPD standardized pre-analytical procedures and stored at Integrated BioBank of Luxembourg. The virtual biobank provides an overview of available CSF, plasma, serum, and DNA samples at each site. Currently, at the central biobank of BIOMARKAPD samples are available from over 400 subjects with normal cognition, mild cognitive impairment (MCI), AD, frontotemporal dementia (FTD), vascular dementia, multiple system atrophy, progressive supranuclear palsy, PD, PD with dementia, and dementia with Lewy bodies. The virtual biobank contains information on over 8,600 subjects with varying diagnoses from 21 local biobanks. A website has been launched to enable sample requests from the central biobank and virtual biobank. 4950 https://doi.org/10.3389/fneur.2015.00216$xR$3Volltext$534 4950 https://nbn-resolving.org/urn:nbn:de:gbv:8-publ-23538$xR$3Volltext$534 4961 https://macau.uni-kiel.de/receive/publ_mods_00002353 5051 610 5550 Alzheimer's disease 5550 biobank 5550 body fluids 5550 cerebrospinal fluid 5550 dementia 5550 neurodegenerative disorders 5550 Parkinson's disease