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Longitudinal, well phenotyped, population-based cohort studies offer unique research opportunities in the context of genome-wide association studies (GWAS), including GWAS for new-onset (incident) cardiovascular disease (CVD) events, the assessment of gene x lifestyle interactions, and evaluating the incremental predictive utility of genetic information in apparently healthy individuals
Scientific Contributions of Population-Based Studies to Cardiovascular Epidemiology in the GWAS Era
GWAS (genome-wide association study)
population
genetic variation
genetic predisposition to disease
risk prediction
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