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Dissertation

Fundamental differences of the hematopoietic growth factors Flt3L and GM-CSF...

The protective role of DCs in intestinal immune response depends on local IFN-I production. IFN-I exerts antimicrobial functions in the intestinal mucosa, including intracellular bacterial killing and antimicrobial peptide production. GM-CSF, but not Flt3L, augments IFN-I dependent antimicrobial effects....