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Dissertation

Characterization of the metalloproteases meprin α and meprin β within the...

Fibrillar collagen type I is the most abundant protein in human body and essential for the formation and strength of bone, skin, and tendon. The assembly of collagen fibrils is initiated by proteolytic enzymes which cleave off the propeptides of procollagen I. Hence, mutations in collagen genes and dysregulation...