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Dissertation

NLRC5 - An NLR member with impact on adaptive and innate immune mechanisms...

NLRC5 was reported to influence the expression of IFNs and NF κB target genes as well as the production of IL 1β. However, its impact is still controversial. NLRC5 was identified to share several features with CIITA, an NLR member that functions as co-transcriptional activator for MHC class II-encoding...