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Dissertation

The role of tyrosine phosphorylation during Dscam1 signaling

The Drosophila Dscam1 gene can be spliced into thousands of different isoforms, providing the basis for a cell surface code: Each cell expresses a distinct subset of 10-50 isoforms, rendering its surface uniquely recognizable. The importance of Dscam1 for axonal and dendritic patterning has been demonstrated...