7 documents found

Article / Chapter
CC BY-NC-ND 3.0
2018

Cholinergic Pathway SNPs and Postural Control in 477 Older Adults.

Objective: To determine whether single nucleotide polymorphisms (SNPs) of the cholinergic system and quantitative parameters of postural control are associated in healthy older adults. This is a cross-sectional analysis from the TREND study. Methods: All participants performed a static postural control...
Lausanne: Frontiers Media SA, 2018
Article / Chapter
CC BY-NC-ND 3.0
2017

Gait Is Associated with Cognitive Flexibility: A Dual-Tasking Study in...

Objectives: To analyze which gait parameters are primarily influenced by cognitive flexibility, and whether such an effect depends on the walking condition used. Design: Cross-sectional analysis. Setting: Tübingen evaluation of Risk factors for Early detection of Neurodegenerative Disorders. Participants:...
Lausanne: Frontiers Media SA, 2017
Article / Chapter
CC BY-NC-ND 3.0
2017

Associations between Early Markers of Parkinson's Disease and Sarcopenia

Introduction: Sarcopenia and Parkinson's disease (PD) are both common age-related syndromes, and there is preliminary evidence that the probability of the co-occurrence of these syndromes within one individual is higher than expected. However, it is unclear to date whether one of the syndromes induces...
Lausanne: Frontiers Media SA, 2017
Article / Chapter
CC BY-NC-ND 3.0
2015

Age and Vascular Burden Determinants of Cortical Hemodynamics Underlying...

BACKGROUND Aging processes and several vascular burden factors have been shown to increase the risk of dementia including Alzheimer's disease. While pathological alterations in dementia precede diagnosis by many years, reorganization of brain processing might temporarily delay cognitive decline. We hypothesized...
San Francisco: PloS one, 2015
Article / Chapter
CC BY-NC-ND 3.0
2014

Mild Parkinsonian Signs in the Elderly – Is There an Association with PD?...

Background: Mild parkinsonian signs (MPS) are common in the elderly population, and have been associated with vascular diseases, mild cognitive impairment and dementia; however their relation to Parkinson’s disease (PD) is unclear. Hypothesizing that individuals with MPS may reflect a pre-stage of...
San Francisco: PloS one, 2014
Article / Chapter
CC BY-NC-ND 3.0
2014

A Neurodegenerative Vascular Burden Index and the Impact on Cognition

Lausanne: Frontiers Media SA, 2014
Article / Chapter
CC BY-NC-ND 3.0
2011

Poor Trail Making Test Performance Is Directly Associated with Altered...

Background: Deterioration of executive functions in the elderly has been associated with impairments in walking performance. This may be caused by limited cognitive flexibility and working memory, but could also be caused by altered prioritization of simultaneously performed tasks. To disentangle these...
San Francisco: PloS one, 2011