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Dissertation
Short version

Regulation of Interleukin-6 Receptor Cell-surface Levels by Internalization...

Receptor cell-surface levels can be regulated by internalization, proteolytic cleavage of the membrane-bound receptor or synthesis of new receptors. Following internalization, the receptors are either recycled to the cell-surface or degraded in the lysosome. I could show that the IL-6R and gp130 are...