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Article / Chapter
CC BY-NC-ND 3.0
2017

The release and trans-synaptic transmission of Tau via exosomes

BACKGROUND Tau pathology in AD spreads in a hierarchical pattern, whereby it first appears in the entorhinal cortex, then spreads to the hippocampus and later to the surrounding areas. Based on this sequential appearance, AD can be classified into six stages ("Braak stages"). The mechanisms and agents...
London: BioMed Central, 2017