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Dissertation

Functional characterization of ORMDL proteins involved in endoplasmic reticulum...

In summary, this study provides evidence that ORMDL proteins are crucial regulators of the UPR, with a particular impact on the ATF6α branch. Especially, ORMDL3 is relevant for maintaining the homeostasis in the ER and the intestinal epithelium. The findings of this study indicate a beneficial regulatory...