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Dissertation
Short version

Influence of Vitamin C on the differentiation and functional plasticity...

Gamma delta (gd) T cells are a numerically small subset of CD3+ T cells in human peripheral blood. They have recently attracted substantial interest as effector cells for cellular immunotherapy, due to their MHC-independent recognition and lysis of many solid tumor and leukemia/lymphoma cells. Depending...
Dissertation
CC BY 4.0

From cold seeps to hot vents on the Nubian/Eurasian plate boundary in the...

Hot and cold fluid expulsions at the seabed are common phenomena in various tectonic settings. Both temperature endmembers play a major role in the element exchange between the lithosphere and the ocean. Understanding the formation and processes involved in fluid generation is the key to understand the...
Dissertation

Analysis of content knowledge and pedagogical content knowledge of pre-service-chemistry...

The intention of this dissertation was the development of adequate, i.e. reliable and valid, test instruments for assessing pre-service teachers’ content knowledge (CK) and pedagogical content knowledge (PCK) were developed. For this, the fundamental concept ‘structure-property-relations’ was chosen...
Dissertation
CC BY-NC-ND 4.0

Computational Modeling and Analytical Tools in Applied Policy Modeling

Policy analysis, the scientific evaluation of policy impact, must include both the technical transformation and political decision process. This analysis is plagued by limited data that leads to model uncertainty. Not only the derived models are uncertain, but also political decision-makers have to...
Dissertation

Impact of meal frequency and energy turnover on the regulation of energy...

Over the last decades, consumption of liquid calories as sugar containing beverages like fruit juices, soft drinks and sweetened coffees increased and became a major risk factor for weight gain. The aim of the first study was to investigate if orange juice consumption together with meals improves energy...
Dissertation

Der parazelluläre Weg des proximalen Tubulus - Untersuchungen regulativer...

Die Homöostase interstitieller Elektrolytkonzentrationen sichert die Funktion der Einzelzelle im Organismus. Über die Ausscheidung von Elektrolyten und Wasser spielt die Niere eine Schlüsselrolle in diesem Prozess. Bereits im proximalen Tubulus erfolgt die trans- sowie parazelluläre Resorption eines...
Dissertation

Untersuchung der hämodynamischen Konsequenzen des transseptalen Zugangs...

Das Mitraclip®-Verfahren wird seit mehreren Jahren erfolgreich zur Behandlung von Patienten mit Mitralklappeninsuffizienz angewandt. Insbesondere bei Patienten mit hohem operativen Risiko stellt es eine gute Alternative zu etablierten kardiochirurgischen Eingriffen dar. Bei der Mitraclip®-Prozedur wird...
Dissertation

Isolation and identification of two repressors, TetR AND LuxR, FOR 3,17β-hsd...

In the 1950s, the importance of microbial degradation was acknowledgedrealised with the emergence of bioinformatics approaches. Numerous reports have investigated the elimination of steroid hormones from contaminated ecosystems by microbial degradation. Due to its capability of degrading multiple toxic...
Dissertation

Reversible Spinschaltung von Eisen(III)-Porphyrinen

Bei Übergangsmetallkomplexen mit einer Elektronenkonfiguration von d4 bis d8 kann die Änderung der Koordinationszahl einen Wechsel des Spinzustands hervorrufen. Beim sogenannten Light-Driven Coordination-Induced Spin State Switch (LD-CISSS) erfolgt dieser Spinwechsel durch die Assoziation und Dissoziation...
Dissertation

Text in Diagrams : Challenges to and Opportunities of Automatic Layout

Visual programming languages based on node-link diagrams are supposedly easy to use and to understand. This is only true, however, if the diagram elements are properly placed - a tedious and time-consuming process if done manually. Automatic graph layout algorithms alleviate users from that burden. Since...