Characterization of inflammatory bowel disease in transgenic mice

Inflammatory bowel disease is a chronic inflammatory disorder of the gastrointestinal tract. In this work the influence of the metalloprotease ADAM17 as well as of IL-6 signaling was analyzed using a DSS-induced colitis model.

Entzündliche Darmerkrankungen gehören zu den chronischen Entzündungen des Gastrointestinaltraktes. In dieser Arbeit wurde der Einfluss der Metalloprotease ADAM17 sowie die IL-6 Signalwege mit Hilfe eines DSS- induzierten Colitismodels näher untersucht.

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