Identification of Functional Genetic Variants in Inflammatory Bowel Disease by Genome and Transcriptome Sequencing

Dissertation dealing with 1) the analysis of the whole genome and transcriptome of a family with a severe case with early onset of Crohn's Disease and 2) the development of an application for the genome-wide analysis of antisense transcription in Next-Generation-Sequencing.

Dissertation, die sich mit der Analyse des gesamten Genoms und Transkriptoms einer Familie mit schwerem Fall und frühem Ausbruch von Morbus Crohn beschäftigt, so wie mit der Entwicklung einer Applikation zur genomweiten Analyse von Antisense-Transkription durch Next-Generation-Sequencing.

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