Functional glycomimetics to explore bacterial adhesion and membrane behaviour: Synthesis and applications
The focus of this thesis lies on carbohydrates as mediators of bacterial adhesion. The process of bacterial adhesion was addressed from two perspectives regarding the bacteria and their adhesive organelles on the one hand and considering the adhesive glycosylated surfaces on the other hand. The glycosylated surfaces were investigated both on the molecular level and in a broader context as glycosylated lipid layers. Hence, this thesis presents the synthesis and analysis of new functional glycomimetics to explore bacterial adhesion and membrane behaviour.