E. coli under stress : Developing a stress-mitigating strategy, and investigating the role of nucleic acid modifications

During their growth, E. coli are exposed to stress conditions. These are damaging, causing cells to function sub-optimally, or triggering a cascade of actions in cells to combat the stress. 

This work explores different aspects of E. coli cells under stress, ranging from mitigating stress placed on cells by genetic circuits, to investigating how nucleic acid modifications change under stress and influence the cellular stress response.

We explore the use of proteolysis tags as a stress-mitigating strategy in cells, and investigate the role of the m6A modification under stress in E. coli, both on mRNA and DNA.


Use and reproduction:

CC BY 4.0

Please note that individual components of the publication may be subject to other licensing or copyright conditions.


Citation style:
Could not load citation form.