The viewpoint of nanolipid vesicles (liposomes, exosomes, and microvesicles) as biosensors in medical health advances

Biosensors are of signi fi cant importance today in the rapid, sensitive, and reliable
detection of biological molecules in many fi elds, including medicine; owing to this
fact, the development of a strong and reliable diagnostic agent is a very interesting
topic. Because of their unique features, among other nanomaterials, lipid-based
vesicles such as liposomes, exosomes, and microvesicles represent a type of
biocompatible and versatile biosensing membrane surface for rapid biomarker
detection and diagnosis of diseases, enhancing the assay sensitivity and
decreasing the detection limit. In this review, we have reviewed the recent
diagnostic application of lipid-based vesicles as biosensing substances in both
conventional and novel techniques for identifying targets, especially in medicine
and biotechnology sciences. Eventually, we have highlighted several recent
promising developments in a new generation of biosensors based on
liposome – nanomaterial hybrids and exosomes for analyzing targets and
possible further advances in the future.


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