Enhancing the skin barrier by emollients in neonates to prevent atopic dermatitis

The importance of the skin barrier for the pathogenesis of atopic dermatitis (AD) is now well accepted. A degraded skin barrier allows the immune system inappropriate access to environmental allergens, leading to sensitization and the initiation of atopic dermatitis. Bland creams and ointments may heal or ameliorate atopic dermatitis and may help in preventing relapses of the disease. Therefore, the idea developed that enhancing the skin barrier in babies by emollients may prevent atopic sensitization. Simpson et al., and Horimukai et al., in 2014 in well-remarked studies showed that emollient use in neonates prevents the development of AD

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