Die Auswirkung zweier Mikrobiota-Bakterien auf das C. elegans-Proteom

Although Chaenorhabditis elegans has been extensively used as a model organism in the laboratory, we know almost nothing about its interaction with naturally associated microbes. Using proteomics, we studied the C. elegans response to two natural Pseudomonas symbionts that protect the roundworms against pathogens. The host response is manifold, involving proteomic changes related to metabolism, pathogen defense, and cell structure, laying the groundwork for exploring mechanisms of microbiota-mediated protection.

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Published in:
BIOspektrum
Publisher:
Springer Science and Business Media LLC
Spektrum, Akad. Verl.
Elsevier, Spektrum, Akad. Verl.
Spektrum, Akad. Verl.
Publishing place:
Heidelberg
Heidelberg
Heidelberg
Heidelberg
Vol.:
30
No.:
7
ISSN:
0947-0867
ISSN:
1868-6249
ISSN:
0947-0867
Pages:
763 - 765
Date Issued:
2024
URN:
urn:nbn:de:gbv:8:3-2026-01139-8
DOI:
10.1007/s12268-024-2340-5
Language:
German
Type of Resource:
Text
Publisher:
Springer Science and Business Media LLC
Keywords:
Caenorhabditis elegans; Pseudomonas; Host–microbe interactions; Proteomics; Symbiosis; Microbiota; Pathogen defense; Host response; Innate immunity; Microbiota-mediated protection
Classification:
Published version
DDC subject of DNB:
570 Life science, Biology
Hosting institution:
Faculties, Faculty of Mathematics and Natural Sciences

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